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NSC 311068

CAS No. 66474-53-1

NSC 311068( NSC311068 )

Catalog No. M15533 CAS No. 66474-53-1

NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5.

Purity : >98% (HPLC)

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Biological Information

Product Name

NSC 311068
Note

Research use only, not for human use.
Brief Description

NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5.
Description

NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo; shows no inhibitory effect on the viability of TET1-low AML (i.e., NB4) cells.
In Vitro

——
In Vivo

——
Synonyms

NSC311068
Pathway

JAK/STAT Signaling
Target

STAT
Recptor

STAT
Research Area

——
Indication

——

Chemical Information

CAS Number

66474-53-1
Formula Weight

278.242
Molecular Formula

C10H6N4O4S
Purity

>98% (HPLC)
Solubility

——
SMILES

C1=CN=C(N=C1)SC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]
Chemical Name

2-((2,4-dinitrophenyl)thio)pyrimidine

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Jiang X, et al. Nat Commun. 2017 Dec 13;8(1):2099.

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