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NSC 311068
CAS No. 66474-53-1
NSC 311068 ( NSC311068 )
Catalog No. M15533 CAS No. 66474-53-1
NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameNSC 311068
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NoteResearch use only, not for human use.
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Brief DescriptionNSC 311068 is a small molecule that directly tragets and inhibits STAT3/5.
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DescriptionNSC 311068 is a small molecule that directly tragets and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo; shows no inhibitory effect on the viability of TET1-low AML (i.e., NB4) cells.
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SynonymsNSC311068
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT
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Research Area——
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Indication——
Chemical Information
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CAS Number66474-53-1
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Formula Weight278.24
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Molecular FormulaC10H6N4O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESC1=CN=C(N=C1)SC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]
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Chemical Name2-((2,4-dinitrophenyl)thio)pyrimidine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jiang X, et al. Nat Commun. 2017 Dec 13;8(1):2099.
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